Therapy switch means a medical practice in which the physician decides to replace the product the patient is currently being treated with by another product. The practice in which a physician decides to switch between different biological molecules is not new. Typically, a switch is driven by a clinical decision to find an appropriate therapy for the patient due to insufficient efficacy and/or tolerability of the previous product.
Biological medicines, including biosimilar medicines, are medical products usually derived from proteins produced using living organisms. Biological medicines are generally larger and more complex than small‑molecule medicines, and the clinical response depends on multiple factors related to the patient, the disease, and the product, which are best assessed by the physician.
